Tyrphostin AG 490

CAS Number: 134036-52-5
Commodity Code: 2926907090
MDL Number: MFCD00209833
Notes: Specific and potent JAK-2 protein tyrosine kinase inhibitor. Also inhibits EGF receptor autophosphorylation, with an IC50 of 100 nM. Inhibits DNA synthesis and cell growth; induces apoptosis. Biochem. Pharmacol. 40: 913-918 (1990).

Chemical Hazard: Toxic/Harmful/Irritant
GHS
Hazard Statements: H301: Toxic if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H312+H332: Harmful in contact with skin or if inhaled
Precautionary Statements: P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}. P301+P310: IF SWALLOWED: Immediately call {{{0|||message=<specify appropriate c: hazard.P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}. P301+P310: IF SWALLOWED: Immediately call {{{0|||message=<specify appropriate c