Tyrphostin AG 490

CAS: 134036-52-5 | BIT1100 | Tyrphostin AG 490

Catalogue Number BIT1100

Synonym(s): N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide, 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide, AG 490, Tyrphostin B42

CAS Number

134036-52-5

Commodity Code

2926907090

MDL Number

MFCD00209833

Notes
Specific and potent JAK-2 protein tyrosine kinase inhibitor. Also inhibits EGF receptor autophosphorylation, with an IC50 of 100 nM. Inhibits DNA synthesis and cell growth; induces apoptosis. Biochem. Pharmacol. 40: 913-918 (1990).
Formula Weight
294.30 g/mol
Melting Point
213-225 °C
Chemical Hazard
Toxic/Harmful/Irritant
GHS
Hazard Statements
H301: Toxic if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H312+H332: Harmful in contact with skin or if inhaled
Precautionary Statements
P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}. P301+P310: IF SWALLOWED: Immediately call {{{0|||message=<specify appropriate c: hazard.P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}. P301+P310: IF SWALLOWED: Immediately call {{{0|||message=<specify appropriate c
MSDS
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Typical Batch COA
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Size
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Quantity
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100mg
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£230.00
Size 100mg
Price £230.00
UK Stock 1 Packs in stock.
US Stock Out of Stock