Synonym(s):
JNK Inhibitor II, 1,9-Pyrazoloanthrone
CAS Number
129-56-6
Commodity Code
2933998090
MDL Number
MFCD00022289
Purity
>99%
Notes
Novel, potent and selective JNK-1,-2, and -3 inhibitor (Ki = 0.19 uM). SP600125 is an ATP-competitive reversible inhibitor with >20-fold selectivity vs. a range of kinases and enzymes tested. Proc. Natl. Acad. Sci. USA 98: 13681-13686 (2001).
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statements
P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}.
P302+P352: IF ON SKIN: Wash with plenty of {{{0|||message=<specify appropriate : hazard.P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}.
P302+P352: IF ON SKIN: Wash with plenty of {{{0|||message=<specify appropriate