Sorafenib

CAS: 284461-73-0 | BISN0134 | Sorafenib

Catalogue Number BISN0134

Synonym(s): 4-[4-[[4-Chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide, BAY 43-9006

CAS Number

284461-73-0

Commodity Code

2933399990

MDL Number

MFCD06411450

Notes
Sorafenib is a multikinase inhibitor of Raf-1 B-Raf and VEGFR-2 with IC50 of 6 nM 22 nM and 90 nM in cell-free assays respectively
Formula Weight
464.82 g/mol
Density
1.46 g/cm³
Melting Point
197 °C
Chemical Hazard
Teratogenic
GHS
Hazard Statements
H360: {{{0|||message=May damage fertility or the unborn child <state specific effect if known>|||default=May damage fertility or the unborn child|||filter=(_)?H_360.+}}} ({{{1|||message=<state route of exposure if it is conclusively proven that no other r
Precautionary Statements
P202: Do not handle until all safety precautions have been read and understood. P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}. P280: Wear {{{0|||message=<s: hazard.P202: Do not handle until all safety precautions have been read and understood. P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}. P280: Wear {{{0|||message=<s
MSDS
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Typical Batch COA
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Size
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500mg
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Size 500mg
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