S63845

CAS: 1799633-27-4 | BISN0043 | S63845

Catalogue Number BISN0043

Synonym(s): α(R)-[[(5S)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(5-fluoro-2-furanyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]methoxy]-benzenepropanoic acid

CAS Number

1799633-27-4

Commodity Code

2934999090

MDL Number

MFCD31382374

Purity
98%
Notes
S63845 specifically binds with high affinity to the BH3-binding groove of MCL1. S63845 potently kills MCL1-dependent cancer cells, including multiple myeloma, leukaemia and lymphoma cells, by activating the BAX/BAK-dependent mitochondrial apoptotic pathway.
Formula Weight
829.26 g/mol
Chemical Hazard
Harmful/Irritant
GHS
Hazard Statements
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statements
P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Re: hazard.P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Re
MSDS
View MSDS
Typical Batch COA
Request COA Information
Request batch specific COA here
Size
UK Stock
UK stock will be shipped internationally
US Stock
US stock is for US shipping only
Price
Quantity
Add to Basket
1mg
1 Packs in stock.
Out of Stock
£60.00
Size 1mg
Price £60.00
UK Stock 1 Packs in stock.
US Stock Out of Stock