This is the most commonly used phorbol ester. It binds to and activates protein kinase C, causes an extremely wide range of effects in cells and tissues, and is a very potent mouse skin tumor promoter. Crit. Rev. Toxicol. 8: 153-197 (1980)
H315: Causes skin irritation.
H351: Suspected of causing cancer ({{{0|||message=<state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>|||filter=(_)?EXP_ROUTE_.+}}}).
Precautionary Statements
P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear {{{0|||message=<specify protection equipmen: hazard.P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear {{{0|||message=<specify protection equipmen