Methyl 5-fluoro-2-hydroxybenzoate
Catalogue Number PC10377
Synonym(s):
Methyl 5-fluoro-2-hydroxybenzoate is a fluorinated organic building block that is commonly used in the preparation of agrochemical and pharmaceutical components. It has been used in the synthesis of a class of macrocyclic ALK inhibitors for the treatment of cancer,[1] and in the synthesis of a br... Read More
- CAS Number
391-92-4
- Commodity Code
2918290090
- MDL Number
MFCD03427141
- Purity
- 98%
- Formula Weight
- 170.14 g/mol
- Melting Point
- 30-34 °C
- Boiling Point
- 50/0.15mm °C
- Flash Point
- 105 °C
- MSDS
- Typical Batch COA
- View
- Request batch specific COA here
Product Description
Methyl 5-fluoro-2-hydroxybenzoate is a fluorinated organic building block that is commonly used in the preparation of agrochemical and pharmaceutical components. It has been used in the synthesis of a class of macrocyclic ALK inhibitors for the treatment of cancer,[1] and in the synthesis of a bridged bicyclic heterocycle as a BTK inhibitor for the treatment of non-Hodgkin’s lymphoma.[2]
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[1] https://worldwide.espacenet.com/patent/search/family/076091584/publication/EP4069700A4?q=pn%3DJP2023504523A
[2] https://worldwide.espacenet.com/patent/search/family/080282666/publication/EP4200283A1?q=pn%3DCN114075190A