Imidazole
Catalogue Number BID0565
Synonym(s):
Imidazole, also known as 1,3-Diazacyclopenta-2,4-diene (CAS: 288-32-4), is a biological buffer used in the purification of His-tagged proteins in immobilised metal affinity chromatography(IMAC). It is also used to elute tagged proteins bound to Ni ions attached to the surface of beads in the chro... Read More
- CAS Number
288-32-4
- Commodity Code
2933299090
- MDL Number
MFCD00005183
- Formula Weight
- 68.08 g/mol
- Density
- 1.03 g/cm³
- Melting Point
- 85-91 °C
- Boiling Point
- 235 °C
- Flash Point
- 145 °C
- MSDS
- Typical Batch COA
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Product Description
Imidazole, also known as 1,3-Diazacyclopenta-2,4-diene (CAS: 288-32-4), is a biological buffer used in the purification of His-tagged proteins in immobilised metal affinity chromatography(IMAC). It is also used to elute tagged proteins bound to Ni ions attached to the surface of beads in the chromatography column. Imidazole has become an important part of many pharmaceuticals. Synthetic imidazoles are present in many fungicides and antifungal, antiprotozoal, and antihypertensive medications.
Imidazole is part of the theophylline molecule, found in tea leaves and coffee beans, which stimulates the central nervous system. It is present in the anticancer medication mercaptopurine, which combats leukemia by interfering with DNA activities.
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