Gefitinib

CAS Number: 184475-35-2
Commodity Code: 2934999090
MDL Number: MFCD04307832
Notes: Gefitinibis an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively, and interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.

Chemical Hazard: Carcinogenic/Teratogenic/Harmful/Irritant
GHS
Hazard Statements: H302: Harmful if swallowed.
H319: Causes serious eye irritation.
H351: Suspected of causing cancer ({{{0|||message=<state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>|||filter=(_)?EXP_ROUTE_.+}}}).
H361
Precautionary Statements: P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}. P301+P312: IF SWALLOWED: Call {{{0|||message=<specify appropriate center>|||def: hazard.P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}. P301+P312: IF SWALLOWED: Call {{{0|||message=<specify appropriate center>|||def