E-64, also known as Epoxysuccinyl-L-leucylamido-(4-guanidino)butane (CAS: 66701-25-5), is a protease inhibitor , and its binding modes with papain, actinidin, cathepsin L, and cathepsin K have been reviewed at the atomic level. E-64 has been widely used as a potent and irreversible (covalent-type... Read More