Synonym(s): (E)-3-Tosylacrylonitrile

CAS Number

19542-67-7

Commodity Code

2926907090

MDL Number

MFCD00712162

Purity

98%

Notes

BAY 11-7082 is a NF-B inhibitor, inhibits TNF-induced IB phosphorylation with IC50 of 10 M in tumor cells. It also inhibits components of the ubiquitin system through inactivating the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13 and UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex).