IRTX is an important new compound that appears to be a very potent vanilloid receptor antagonist. IRTX binds to the VR1 receptor with high affinity (Kd = 4.3 nM) but does not induce RTX- or capsaicin-like effects in Xenopus laevis oocytes expressing VR1. Mol. Pharm. 59: 9-15 (2001).
May cause respiratory irritation.|Causes skin irritation.|Causes serious eye irritation.
Precautionary Statements
Use only outdoors or in a well-ventilated area.|Avoid breathing dust/fumes.|Wear protective gloves: hazard.Use only outdoors or in a well-ventilated area.|Avoid breathing dust/fumes.|Wear protective gloves
protective clothing: hazard. protective clothing
eye protection and face protection.|Wash all exposed external body areas thoroughly after handling.|IF IN EYES: Rinse cautiously with : hazard. eye protection and face protection.|Wash all exposed external body areas thoroughly after handling.|IF IN EYES: Rinse cautiously with
