5-Bromo-2-iodobenzyl bromide
Catalogue Number OR17110
Synonym(s): 4-Bromo-2-(bromomethyl)-1-iodobenzene, alpha,5-Dibromo-2-iodotoluene
5-Bromo-2-iodobenzyl bromide (CAS: 495414-06-7) is an organic building block with applications in the preparation of pharmaceutical and agrochemical components. It can be used as an elect... Read More
- CAS Number
495414-06-7
- Commodity Code
2903998090
- MDL Number
MFCD12025360
- Purity
- 95+%
- Formula Weight
- 375.83 g/mol
- Melting Point
- 83-85 °C
- Boiling Point
- 335/760mm °C
- Flash Point
- 156 °C
- Chemical Hazard
- Corrosive/Harmful
- GHS
-
- Hazard Statements
-
H314: Causes severe skin burns and eye damage.
H335: May cause respiratory irritation.
- Precautionary Statements
-
P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear {{{0|||message=<specify protection equipmen: hazard.P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear {{{0|||message=<specify protection equipmen
- MSDS
- Typical Batch COA
- View
- Request batch specific COA here
Product Description
5-Bromo-2-iodobenzyl bromide (CAS: 495414-06-7) is an organic building block with applications in the preparation of pharmaceutical and agrochemical components. It can be used as an electrophilic partner in a variety of palladium-catalysed cross coupling reactions and as a reagent in standard nucleophilic substitutions. It has been used in the synthesis of glucagon-like peptide 1 receptor agonists to treat type II diabetes,[1] and in the synthesis of 2-methylquinazolines as pharmacologically-active compounds.[2]
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[1] https://worldwide.espacenet.com/patent/search/family/082016585/publication/TW202310838A?q=pn%3DTW202310838
[2] https://worldwide.espacenet.com/patent/search/family/061972486/publication/US2022235013A1?q=pn%3DUS2022235013