5-Bromo-2-iodobenzyl bromide

CAS: 495414-06-7 | OR17110 | 5-Bromo-2-iodobenzyl bromide

Catalogue Number OR17110

Synonym(s): 4-Bromo-2-(bromomethyl)-1-iodobenzene, alpha,5-Dibromo-2-iodotoluene

5-Bromo-2-iodobenzyl bromide (CAS: 495414-06-7) is an organic building block with applications in the preparation of pharmaceutical and agrochemical components. It can be used as an elect... Read More

CAS Number

495414-06-7

Commodity Code

2903998090

MDL Number

MFCD12025360

Purity
95+%
Formula Weight
375.83 g/mol
Melting Point
83-85 °C
Boiling Point
335/760mm °C
Flash Point
156 °C
Chemical Hazard
Corrosive/Harmful
GHS
Hazard Statements
H314: Causes severe skin burns and eye damage.
H335: May cause respiratory irritation.
Precautionary Statements
P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}. P271: Use only outdoors or in a well-ventilated area. P280: Wear {{{0|||message=<specify protection equipmen: hazard.P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}. P271: Use only outdoors or in a well-ventilated area. P280: Wear {{{0|||message=<specify protection equipmen
MSDS
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Typical Batch COA
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Size
UK Stock
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US Stock
US stock is for US shipping only
Price
Quantity
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250mg
In Stock
Leadtime: 1-2 weeks
£27.00
1g
In Stock
Leadtime: 1-2 weeks
£63.00
Size 250mg
Price £27.00
UK Stock
In Stock
US Stock 1 Pack In Stock
Size 1g
Price £63.00
UK Stock
In Stock
US Stock 1 Pack In Stock

Product Description

5-Bromo-2-iodobenzyl bromide (CAS: 495414-06-7) is an organic building block with applications in the preparation of pharmaceutical and agrochemical components. It can be used as an electrophilic partner in a variety of palladium-catalysed cross coupling reactions and as a reagent in standard nucleophilic substitutions. It has been used in the synthesis of glucagon-like peptide 1 receptor agonists to treat type II diabetes,[1] and in the synthesis of 2-methylquinazolines as pharmacologically-active compounds.[2]


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[1] https://worldwide.espacenet.com/patent/search/family/082016585/publication/TW202310838A?q=pn%3DTW202310838

[2] https://worldwide.espacenet.com/patent/search/family/061972486/publication/US2022235013A1?q=pn%3DUS2022235013