4-(Hydroxymethyl)tetrahydro-2H-pyran is an organic reagent with applications in the agrochemical and pharmaceutical industries. It has been used in nucleophilic aromatic substitution reactions with aryl halides in the preparation of RORγ inverse agonists for the treatment of psoriasis,[1] and CDK... Read More
4-(Hydroxymethyl)tetrahydro-2H-pyran is an organic reagent with applications in the agrochemical and pharmaceutical industries. It has been used in nucleophilic aromatic substitution reactions with aryl halides in the preparation of RORγ inverse agonists for the treatment of psoriasis,[1] and CDK2 inhibitors as potential drug candidates for the treatment of cancer.[2]
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1) https://pubs.acs.org/doi/10.1021/acs.oprd.9b00147#
2) https://worldwide.espacenet.com/patent/search/family/082655170/publication/WO2023278326A1?q=pn%3DWO2023278326
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