4-(Hydroxymethyl)tetrahydro-2H-pyran
Catalogue Number OR10585
Synonym(s): (Tetrahydro-2H-pyran-4-yl)methanol, (Oxan-4-yl)methanol
4-(Hydroxymethyl)tetrahydro-2H-pyran is an organic reagent with applications in the agrochemical and pharmaceutical industries. It has been used in nucleophilic aromatic substitution reactions with aryl halides in the preparation of RORγ inverse agonists for the treatment of psoriasis,[1] and CDK... Read More
- CAS Number
14774-37-9
- Commodity Code
2932990090
- MDL Number
MFCD00457804
- Purity
- 98%
- Formula Weight
- 116.16 g/mol
- Boiling Point
- 105-110/20mm °C
- Flash Point
- >61 °C
- Chemical Hazard
- Irritant
- GHS
-
- Hazard Statements
-
May cause respiratory irritation.|Causes skin irritation.|Causes serious eye irritation.
- Precautionary Statements
-
Use only outdoors or in a well-ventilated area.|Avoid breathing mist/vapours/spray.|Wear protective gloves: hazard.Use only outdoors or in a well-ventilated area.|Avoid breathing mist/vapours/spray.|Wear protective gloves
protective clothing: hazard. protective clothing
eye protection and face protection.|Wash all exposed external body areas thoroughly after handling.|IF IN EYES: Rinse cautious: hazard. eye protection and face protection.|Wash all exposed external body areas thoroughly after handling.|IF IN EYES: Rinse cautious
- MSDS
- Typical Batch COA
- View
- Request batch specific COA here
Product Description
4-(Hydroxymethyl)tetrahydro-2H-pyran is an organic reagent with applications in the agrochemical and pharmaceutical industries. It has been used in nucleophilic aromatic substitution reactions with aryl halides in the preparation of RORγ inverse agonists for the treatment of psoriasis,[1] and CDK2 inhibitors as potential drug candidates for the treatment of cancer.[2]
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1) https://pubs.acs.org/doi/10.1021/acs.oprd.9b00147#
2) https://worldwide.espacenet.com/patent/search/family/082655170/publication/WO2023278326A1?q=pn%3DWO2023278326