3-(Difluoromethyl)aniline (368-99-0) is a fluorinated organic building block used in the synthesis of dyes and pharmaceutical components. The compound has been used in synthetic research to target various drug receptors, including 4,6-pyrimidine analogues as anticancer agents,[1] MAP4K1 inhibitor... Read More
3-(Difluoromethyl)aniline (368-99-0) is a fluorinated organic building block used in the synthesis of dyes and pharmaceutical components. The compound has been used in synthetic research to target various drug receptors, including 4,6-pyrimidine analogues as anticancer agents,[1] MAP4K1 inhibitors for the treatment of immunology disorders,[2] and RXFP1 modulators for the treatment of heart failure.[3]
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1) https://www.sciencedirect.com/science/article/abs/pii/S0223523422009874?via%3Dihub
2) https://worldwide.espacenet.com/patent/search?q=pn%3DJP2021506735A
3) https://worldwide.espacenet.com/patent/search/family/078916968/publication/WO2022122773A1?q=pn%3DWO2022122773
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