3-Chloro-5-methoxyaniline
Catalogue Number OR313073
Synonym(s):
3-Chloro-5-methoxyaniline (CAS: 10272-06-7) is an organic building block used in the synthesis of pharmaceutical and agrochemical components. It can be used as an electrophilic partner in... Read More
- CAS Number
10272-06-7
- Commodity Code
2921410090
- MDL Number
MFCD11035922
- Formula Weight
- 157.60 g/mol
- Chemical Hazard
- Harmful/Irritant
- GHS
-
- Hazard Statements
-
May cause respiratory irritation.|Harmful if swallowed.|Causes skin irritation.|Causes serious eye irritation.
- Precautionary Statements
-
Use only outdoors or in a well-ventilated area.|Avoid breathing dust/fumes.|Wash all exposed external body areas thoroughly after handling.|Do not eat: hazard.Use only outdoors or in a well-ventilated area.|Avoid breathing dust/fumes.|Wash all exposed external body areas thoroughly after handling.|Do not eat
drink or smoke when using this product.|Wear protective gloves: hazard. drink or smoke when using this product.|Wear protective gloves
protective clothing: hazard. protective clothing
eye protection and: hazard. eye protection and
- MSDS
- Typical Batch COA
- View
- Request batch specific COA here
Product Description
3-Chloro-5-methoxyaniline (CAS: 10272-06-7) is an organic building block used in the synthesis of pharmaceutical and agrochemical components. It can be used as an electrophilic partner in a variety of palladium-catalysed cross-coupling reactions and as a nucleophilic reagent in amide couplings. It has been used in the synthesis of ALK2 kinase inhibitors for the treatment of cancer,[1] and in the synthesis of small molecule KRAS G12C inhibitors.[2]
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1) https://worldwide.espacenet.com/patent/search/family/064659499/publication/US11661426B2?q=pn%3DUS11661426
2) https://worldwide.espacenet.com/patent/search/family/083847491/publication/WO2022232320A1?q=pn%3DWO2022232320