3-Bromo-2-methoxyaniline

CAS: 116557-46-1 | OR17601 | 3-Bromo-2-methoxyaniline

Catalogue Number OR17601

Synonym(s): 2-Amino-6-bromoanisole, 3-Bromo-o-anisidine

3-Bromo-2-methoxyaniline (CAS: 116557-46-1) is an organic building block used in the preparation of agrochemical and pharmaceutical components. It can be used as an electrophilic partner... Read More

CAS Number

116557-46-1

Commodity Code

2922290090

MDL Number

MFCD13186737

Formula Weight
202.05 g/mol
Chemical Hazard
Toxic/Harmful/Irritant
GHS
Hazard Statements
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statements
P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}. P271: Use only outdoors or in a well-ventilated area. P280: Wear {{{0|||message=<specify protection eq: hazard.P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}. P271: Use only outdoors or in a well-ventilated area. P280: Wear {{{0|||message=<specify protection eq
MSDS
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Typical Batch COA
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Size
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1g
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Leadtime: 1-2 weeks
£12.00
5g
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£35.00
10g
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Leadtime: 1-2 weeks
£60.00
Size 1g
Price £12.00
UK Stock
In Stock
US Stock In Stock
Size 5g
Price £35.00
UK Stock
5 Packs in stock.
US Stock 1 Pack In Stock
Size 10g
Price £60.00
UK Stock
2 Packs in stock.
US Stock Out of Stock

Product Description

3-Bromo-2-methoxyaniline (CAS: 116557-46-1) is an organic building block used in the preparation of agrochemical and pharmaceutical components. It can be used as an electrophilic partner in a variety of cross coupling reactions, or as a nucleophilic reagent in amide couplings. It has been used in the synthesis of JAK2 inhibitors to treat autoimmune diseases,[1] and in the synthesis of aryl-substituted pyridines as pharmacologically-active compounds.[2]

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1) https://worldwide.espacenet.com/patent/search/family/083319069/publication/WO2023027948A1?q=pn%3DWO2023027948

2) https://worldwide.espacenet.com/patent/search/family/075787305/publication/EP4136073A1?q=pn%3DCN115702145A