2',3'-Difluoroacetophenone
Catalogue Number PC2574
Synonym(s): 1-(2,3-Difluorophenyl)ethan-1-one
2’,3’-Difluoroacetophenone (CAS: 18355-80-1) is an aromatic building block which can be used in the preparation of pharmaceutical and agrochemical components. It has been used i... Read More
- CAS Number
18355-80-1
- Commodity Code
2914790090
- MDL Number
MFCD00061274
- Purity
- 98%
- Formula Weight
- 156.13 g/mol
- Boiling Point
- 85/20mm °C
- Ref Index
- 1.489
- Chemical Hazard
- Irritant
- GHS
-
- Hazard Statements
-
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
- Precautionary Statements
-
P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear {{{0|||message=<specify protection eq: hazard.P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear {{{0|||message=<specify protection eq
- MSDS
- FTIR
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- Typical Batch COA
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Product Description
2’,3’-Difluoroacetophenone (CAS: 18355-80-1) is an aromatic building block which can be used in the preparation of pharmaceutical and agrochemical components. It has been used in the synthesis of a class of RIPK1 inhibitors for the treatment of neurodegenerative diseases and in the synthesis of benzopyrazole analogues as ROCK inhibitors for the treatment of autoimmune disorders.[1.2]
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[1] https://worldwide.espacenet.com/patent/search/family/074852257/publication/US11718612B2?q=pn%3DUS11718612
[2] https://worldwide.espacenet.com/patent/search/family/068239949/publication/US11345678B2?q=pn%3DUS11345678