2',3'-Difluoroacetophenone

CAS: 18355-80-1 | PC2574 | 2',3'-Difluoroacetophenone

Catalogue Number PC2574

Synonym(s): 1-(2,3-Difluorophenyl)ethan-1-one

2’,3’-Difluoroacetophenone (CAS: 18355-80-1) is an aromatic building block which can be used in the preparation of pharmaceutical and agrochemical components. It has been used i... Read More

CAS Number

18355-80-1

Commodity Code

2914790090

MDL Number

MFCD00061274

Purity
98%
Formula Weight
156.13 g/mol
Boiling Point
85/20mm °C
Ref Index
1.489
Chemical Hazard
Irritant
GHS
Hazard Statements
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statements
P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}. P271: Use only outdoors or in a well-ventilated area. P280: Wear {{{0|||message=<specify protection eq: hazard.P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}. P271: Use only outdoors or in a well-ventilated area. P280: Wear {{{0|||message=<specify protection eq
MSDS
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FTIR
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Typical Batch COA
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Size
UK Stock
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US Stock
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Price
Quantity
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5g
In Stock
In Stock
£10.00
25g
In Stock
1 Pack In Stock
£34.00
100g
In Stock
Out of Stock
£126.00
Size 5g
Price £10.00
UK Stock
In Stock
US Stock In Stock
Size 25g
Price £34.00
UK Stock
In Stock
US Stock 1 Pack In Stock
Size 100g
Price £126.00
UK Stock
In Stock
US Stock Out of Stock

Product Description

2’,3’-Difluoroacetophenone (CAS: 18355-80-1) is an aromatic building block which can be used in the preparation of pharmaceutical and agrochemical components. It has been used in the synthesis of a class of RIPK1 inhibitors for the treatment of neurodegenerative diseases and in the synthesis of benzopyrazole analogues as ROCK inhibitors for the treatment of autoimmune disorders.[1.2]

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[1] https://worldwide.espacenet.com/patent/search/family/074852257/publication/US11718612B2?q=pn%3DUS11718612

[2] https://worldwide.espacenet.com/patent/search/family/068239949/publication/US11345678B2?q=pn%3DUS11345678