2-(Difluoromethyl)aniline hydrochloride
Catalogue Number PC57056
Synonym(s): 2-Aminobenzal fluoride hydrochloride, alpha,alpha-Difluoro-o-toluidine hydrochloride
2-(Difluoromethyl)aniline hydrochloride is a fluorinated aromatic building block that is commonly used in the preparation of pharmaceutical and agrochemical components. It has been used in the synthesis of biaryl and 1,2,4-triazolones dihydroorotate dehydrogenase inhibitors for the treatment of a... Read More
- CAS Number
1422344-12-4
- Commodity Code
2921420090
- MDL Number
MFCD23378513
- Formula Weight
- 179.59 g/mol
- Chemical Hazard
- Harmful/Irritant
- GHS
-
- Hazard Statements
-
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
- Precautionary Statements
-
P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear {{{0|||message=<specify protection eq: hazard.P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear {{{0|||message=<specify protection eq
- MSDS
- FTIR
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- Typical Batch COA
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Product Description
2-(Difluoromethyl)aniline hydrochloride is a fluorinated aromatic building block that is commonly used in the preparation of pharmaceutical and agrochemical components. It has been used in the synthesis of biaryl and 1,2,4-triazolones dihydroorotate dehydrogenase inhibitors for the treatment of acute myelogenous leukaemia.[1,2]
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1) https://worldwide.espacenet.com/patent/search/family/072964759/publication/EP4041714A1?q=pn%3DCN114630822A
2) https://worldwide.espacenet.com/patent/search/family/060293935/publication/WO2018077944A2?q=pn%3DWO2018077944