2-(Difluoromethyl)aniline hydrochloride is a fluorinated aromatic building block that is commonly used in the preparation of pharmaceutical and agrochemical components. It has been used in the synthesis of biaryl and 1,2,4-triazolones dihydroorotate dehydrogenase inhibitors for the treatment of a... Read More
2-(Difluoromethyl)aniline hydrochloride is a fluorinated aromatic building block that is commonly used in the preparation of pharmaceutical and agrochemical components. It has been used in the synthesis of biaryl and 1,2,4-triazolones dihydroorotate dehydrogenase inhibitors for the treatment of acute myelogenous leukaemia.[1,2]
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1) https://worldwide.espacenet.com/patent/search/family/072964759/publication/EP4041714A1?q=pn%3DCN114630822A
2) https://worldwide.espacenet.com/patent/search/family/060293935/publication/WO2018077944A2?q=pn%3DWO2018077944
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