2-(Difluoromethyl)-4-chloro-1H-benzimidazole

Product Description

2(-Difluoromethyl)-4-chloro-1H-benzimidazole (CAS 1342424-21-8) is a heterocyclic building block which can be used in the preparation of pharmaceutical and agrochemical components. It can be used in the synthesis of a class of benzimidazole PI3K inhibitors for the treatment of cardiovascular diseases,[1] and in a method for treating cancer by combining a PI3Kβ inhibitor with an 0X40 binding protein.[2]

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[1] https://worldwide.espacenet.com/patent/search/family/045925614/publication/CA2812608C?q=pn%3DCA2812608C

[2] https://worldwide.espacenet.com/patent/search/family/065012044/publication/WO2019106605A1?q=pn%3DWO2019106605