2-(Difluoromethyl)-4-chloro-1H-benzimidazole
Catalogue Number PC32936
Synonym(s):
2(-Difluoromethyl)-4-chloro-1H-benzimidazole (CAS 1342424-21-8) is a heterocyclic building block which can be used in the preparation of pharmaceutical and agrochemical components. I... Read More
- CAS Number
1342424-21-8
- Commodity Code
2933998090
- MDL Number
MFCD20390926
- Formula Weight
- 202.59 g/mol
- Chemical Hazard
- Harmful/Irritant
- GHS
-
- Hazard Statements
-
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H302+H312+H332: Harmful if swallowed, in contact with skin or if inhaled
- Precautionary Statements
-
P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}.
P301+P312: IF SWALLOWED: Call {{{0|||message=<specify appropriate center>|||def: hazard.P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}.
P301+P312: IF SWALLOWED: Call {{{0|||message=<specify appropriate center>|||def
- MSDS
- Typical Batch COA
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Product Description
2(-Difluoromethyl)-4-chloro-1H-benzimidazole (CAS 1342424-21-8) is a heterocyclic building block which can be used in the preparation of pharmaceutical and agrochemical components. It can be used in the synthesis of a class of benzimidazole PI3K inhibitors for the treatment of cardiovascular diseases,[1] and in a method for treating cancer by combining a PI3Kβ inhibitor with an 0X40 binding protein.[2]
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[1] https://worldwide.espacenet.com/patent/search/family/045925614/publication/CA2812608C?q=pn%3DCA2812608C
[2] https://worldwide.espacenet.com/patent/search/family/065012044/publication/WO2019106605A1?q=pn%3DWO2019106605