2-Bromo-6-methylanisole

CAS: 52200-69-8 | OR40672 | 2-Bromo-6-methylanisole

Catalogue Number OR40672

Synonym(s): 3-Bromo-2-methoxytoluene, 1-Bromo-2-methoxy-3-methylbenzene, 2-Bromo-6-methylphenyl methyl ether

2-Bromo-6-methylanisole (CAS: 52200-69-8) is an organic building block used in the preparation of agrochemical and pharmaceutical components. It can be used as an electrophilic partner in... Read More

CAS Number

52200-69-8

Commodity Code

2909303890

MDL Number

MFCD12547891

Purity
98%
Formula Weight
201.06 g/mol
Density
1.41 g/cm³
Melting Point
-39 to -36 °C
Boiling Point
62-63/3mm °C
Ref Index
1.5472
Chemical Hazard
Irritant
GHS
Hazard Statements
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statements
P261: Avoid breathing <dust/fumes/gas/mist/vapours/spray>. P271: Use only outdoors or in a well-ventilated area. P280: Wear <protective gloves/protective clothing/eye protection/face protection>.: hazard.P261: Avoid breathing <dust/fumes/gas/mist/vapours/spray>. P271: Use only outdoors or in a well-ventilated area. P280: Wear <protective gloves/protective clothing/eye protection/face protection>.
MSDS
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Typical Batch COA
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Size
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Price
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1g
In Stock
Leadtime: 1-2 weeks
£30.00
5g
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Leadtime: 1-2 weeks
£122.00
25g
1 Packs in stock.
Leadtime: 1-2 weeks
£427.00
Size 1g
Price £30.00
UK Stock
In Stock
US Stock In Stock
Size 5g
Price £122.00
UK Stock
In Stock
US Stock 1 Pack In Stock
Size 25g
Price £427.00
UK Stock
1 Packs in stock.
US Stock Out of Stock

Product Description

2-Bromo-6-methylanisole (CAS: 52200-69-8) is an organic building block used in the preparation of agrochemical and pharmaceutical components. It can be used as an electrophilic partner in a variety of palladium-catalysed cross coupling reactions. It has also been used in the synthesis of heterocyclic TYK2 inhibitors for the treatment of autoimmune and inflammatory diseases,[1] and in the synthesis of PLpro inhibitors as anti-virals.[2]

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1) https://worldwide.espacenet.com/patent/search/family/061906011/publication/EP3526222A1?q=pn%3DJP2023106606A

2) https://worldwide.espacenet.com/patent/search/family/080937042/publication/WO2022189810A1?q=pn%3DWO2022189810